Nitrazepam has long been affiliated with severe hepatic Problems, similar to other nitrobenzodiazepines. Nitrobenzodiazepines such as nitrazepam, nimetazepam, flunitrazepam, and clonazepam are more toxic towards the liver than other benzodiazepines as They may be metabolically activated by CYP3A4 which may end up in cytotoxicity.Nitrazepam 10mg Tab